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Invitrogen™ Phospho-RSK3 (Thr356, Ser360) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585817

Catalog No. PIPA585817


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Description

Description

Keep as concentrated solution. Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%). Positive Control: EGF treated A431. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It is believed that RPS6KA2 is a signal-transducing intermediate in the cellular response to several growth factors. It is found in many tissues, but in higher levels in lung and skeletal muscle. The p90 ribosomal S6 kinases (RSK)1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits and may have a tonic regulation on G-protein coupled signaling.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-RSK3 (Thr356, Ser360)
Polyclonal
Unconjugated
RPS6KA2
90 kDa ribosomal protein S6 kinase 2; 90kDa; D17Wsu134e; HU-2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1C; MAPKAPK1C; MAPKAPK-1c; mitogen-activated protein kinase-activated protein kinase 1C; p90rsk; p90-RSK 2; p90RSK2; p90-RSK3; pp90rsk; pp90RSK3; Protein-tyrosine kinase Mpk-9; ribosomal protein S6 kinase A2; ribosomal protein S6 kinase alpha 2; ribosomal protein S6 kinase alpha-2; ribosomal protein S6 kinase polypeptide 2; ribosomal protein S6 kinase, 90kD, polypeptide 2; ribosomal protein S6 kinase, 90kDa, polypeptide 2; ribosomal protein S6 kinase, polypeptide 2; ribosomal S6 kinase 3; Rps6ka2; Rps6ka-rs1; RSK; Rsk3; RSK-3; S6K-alpha; S6K-alpha 2; S6K-alpha2; S6K-alpha-2
Rabbit
Antigen Affinity Chromatography
RUO
6196
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
0.21 mg/mL
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Q15349
RPS6KA2
Carrier-protein conjugated synthetic peptide corresponding to residues around human RSK3 (phospho Thr356/Ser360).
100 μL
Primary
Human
Antibody
IgG
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