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Invitrogen™ Phospho-RXRA (Ser260) Polyclonal Antibody
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Catalog No. PIPA5105942
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100 μL
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PIPA5105942 100 μL
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Catalog No. PIPA5105942 Supplier Invitrogen™ Supplier No. PA5105942
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of RXR alpha only when phosphorylated at Ser260.

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-RXRA (Ser260)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Rxra
Gene Accession No. P19793, P28700, Q05343
Gene Alias 9530071D11Rik; Nr2b1; Nuclear receptor subfamily 2 group B member 1; retinoic acid receptor RXR-alpha; retinoid X nuclear receptor alpha; retinoid X receptor; retinoid X receptor alpha; retinoid X receptor, alpha; rxr alpha; RXR alpha 1; Rxra; RXRalpha1
Gene Symbols Rxra
Host Species Rabbit
Immunogen A synthesized peptide derived from human RXRA(Accession P19793), corresponding to amino acid residues around phosphorylated Ser260.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20181, 25271, 6256
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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