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Invitrogen™ Phospho-Ship2 (Tyr1135) Recombinant Rabbit Monoclonal Antibody (Ship2Y1135-1D2), APC
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Catalog No. PIMA537045
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PIMA537045 10 Tests
PIMA528014 100 Tests
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Catalog No. PIMA537045 Supplier Invitrogen™ Supplier No. MA537045
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Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodeling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.
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Specifications

Antigen Phospho-Ship2 (Tyr1135)
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone Ship2Y1135-1D2
Conjugate APC
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene INPPL1
Gene Accession No. O15357, Q6P549
Gene Alias 51C; 51C protein; ablSH3-binding protein; inositol polyphosphate phosphatase like 1; inositol polyphosphate phosphatase-like 1; inositol polyphosphate phosphatase-like protein 1; Inppl1; INPPL-1; NS1; OPSMD; Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2; protein 51C; PTP2C; SH2 domain-containing inositol 5'-phosphatase 2; SH2 domain-containing inositol phosphatase 2; SH2 domain-containing inositol-5'-phosphatase 2; SH2-containing inositol phosphatase 2; SHIP2; SHIP-2; SHP-2; SH-PTP2
Gene Symbols INPPL1
Host Species Rabbit
Immunogen A synthetic phospho-peptide corresponding to residues surrounding Tyr1135 of human phospho Ship2.
Purification Method Protein A/G
Quantity 10 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16332, 3636
Target Species Human, Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG κ
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