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Invitrogen™ Phospho-SLC39A7 (Ser275, Ser276) Polyclonal Antibody
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Catalog No. PIPA5114678
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PIPA5114678 100 μL
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Catalog No. PIPA5114678 Supplier Invitrogen™ Supplier No. PA5114678
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of ZIP7 only when phosphorylated at Ser275/276.

The zinc transporter ZIP7, also known as SLC39A7, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP7 was initially identified while characterizing genes in the major histocompatibility complex on chromosome 17. ZIP7 mRNA is abundantly and widely expressed and the protein localizes to the Golgi apparatus. It functions to transport intracellular zinc from the Golgi apparatus to the cytoplasm of the cell. ZIP7 expression is expressed by zinc. ZIP7 has been suggested to act a hub for tyrosine kinase activation and may thus be a potential therapeutic target for diseases such as cancer where prevention of tyrosine kinase activation would be advantageous.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-SLC39A7 (Ser275, Ser276)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene SLC39A7
Gene Accession No. Q31125, Q92504
Gene Alias AA408174; AI117660; AL024048; D6S115E; D6S2244E; DADB-100D22.3; H2-K region expressed gene 4; H-2Ke4; H2-KE4; Histidine-rich membrane protein; histidine-rich membrane protein Ke4; HKE4; HLA class II region expressed gene KE4; KE4; Ke-4; Ke4 gene; Ke4 gene, mouse, human homolog of; really interesting new gene 5 protein; Ring5; RT1 class I, locus Ke4; RT1 region expressed gene KE4; Rt1Ke4; RT1-Ke4; Slc39a7; solute carrier family 39 (zinc transporter), member 7; solute carrier family 39 member 7; Unknown (protein for MGC:142379); zinc transporter SLC39A7; ZIP7; zrt-, Irt-like protein 7
Gene Symbols SLC39A7
Host Species Rabbit
Immunogen A synthesized peptide derived from human ZIP7 around the phosphorylation site of Ser275/276.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14977, 294281, 7922
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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