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Invitrogen™ Phospho-SMAD5 (Ser463, Ser465) Polyclonal Antibody
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Catalog No. PIPA5114644
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PIPA5114644 100 μL
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Catalog No. PIPA5114644 Supplier Invitrogen™ Supplier No. PA5114644
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Smad5 only when phosphorylated at Ser463/465.

SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, 2, 5, 8 and 9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and 7). SMAD1, 5, 8 and 9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-SMAD5 (Ser463, Ser465)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene SMAD5
Gene Accession No. P97454, Q99717, Q9R1V3
Gene Alias 1110051M15Rik; AI451355; DKFZp781C1895; DKFZp781O1323; dwarfin-C; DWFC; Dwf-C; hSmad5; JV5-1; MAD homolog 5; MAD, mothers against decapentaplegic homolog 5; Madh5; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 5; mSmad5; MusMLP; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; SMAD 5; SMAD family member 5; SMAD, mothers against DPP homolog 5; SMAD5
Gene Symbols SMAD5
Host Species Rabbit
Immunogen A synthesized peptide derived from human Smad5 around the phosphorylation site of Ser463/465.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17129, 4090, 59328
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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