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Phospho-SQSTM1 (Thr269, Ser272) Polyclonal Antibody, Invitrogen™

Catalog No. PIPA5104657
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PIPA5104657 100 μL
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Catalog No. PIPA5104657 Supplier Thermo Scientific Supplier No. PA5104657

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of SQSTM1/p62 only when phosphorylated at Thr269/Ser272.

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-SQSTM1 (Thr269, Ser272)
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Sqstm1
Gene Accession No. O08623, Q13501, Q64337
Gene Alias A170; EBI3-associated protein of 60 kDa; EBI3-associated protein p60; EBIAP; FTDALS3; hypothetical protein 1; ORCA; OSF-6; Osi; OSIL; oxidative stress induced; oxidative stress induced like; p60; p62; p62B; PDB3; phosphotyrosine independent ligand for the Lck SH2 domain p62; phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; PKC-zeta-interacting protein; protein kinase C-zeta-interacting protein; sb:cb621; Sequestosome 1; sequestosome-1; Sqstm1; STAP; STONE14; ubiquitin-binding protein p62; Unknown (protein for MGC:127197); zgc:85784; ZIP; ZIP3
Gene Symbols Sqstm1
Host Species Rabbit
Immunogen A synthesized peptide derived from human SQSTM1(Accession Q13501), corresponding to amino acid residues around phosphorylated Ser272.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 113894, 18412, 8878
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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