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Phospho-Src (Y416) Rabbit anti-Human, Clone: 1246F, R&D Systems™
Recombinant Monoclonal Antibody
$148.35 - $329.00
Specifications
| Antigen | Src |
|---|---|
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with Sodium Azide |
| Format | Purified |
| Clone | 1246F |
| Applications | Immunocytochemistry, Western Blot |
Description
The Src family of proteins are intracellular tyrosine kinases involved in cell proliferation, differentiation, motility, and survival. Src family activity is regulated by tyrosine phosphorylation at two sites with opposing effects. Autophosphorylation in the activation loop of the kinase domain (Y419 of human Src) upregulates the enzyme, while phosphorylation in the C-terminal tail (Y530 of human Src) downregulates activity.Specifications
| Src | |
| Purified | |
| Immunocytochemistry, Western Blot | |
| Rabbit | |
| Protein A or G purified from cell culture supernatant | |
| RUO |
| Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with Sodium Azide | |
| 1246F | |
| Unconjugated | |
| IgG | |
| Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution. |
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