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Phospho-Src (Y416) Rabbit anti-Human, Clone: 1246F, R&D Systems™

Recombinant Monoclonal Antibody

$148.35 - $329.00

Specifications

Antigen Src
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with Sodium Azide
Format Purified
Clone 1246F
Applications Immunocytochemistry, Western Blot
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
MAB2685 View Documents R&D Systems
MAB2685
100 ug Each for $329.00
Add to cart
 
MAB2685SP View Documents R&D Systems
MAB2685SP
25 ug Each for $148.35
Add to cart
 
Description

Description

The Src family of proteins are intracellular tyrosine kinases involved in cell proliferation, differentiation, motility, and survival. Src family activity is regulated by tyrosine phosphorylation at two sites with opposing effects. Autophosphorylation in the activation loop of the kinase domain (Y419 of human Src) upregulates the enzyme, while phosphorylation in the C-terminal tail (Y530 of human Src) downregulates activity.
Specifications

Specifications

Src
Purified
Immunocytochemistry, Western Blot
Rabbit
Protein A or G purified from cell culture supernatant
RUO
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with Sodium Azide
1246F
Unconjugated
IgG
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
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