Phospho-Stat2 (Tyr690) Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-5393	100 μL

Catalog No. 50-198-5393 Supplier Bioss Supplier No. BS3428R

Description

Rabbit Polyclonal Antibody

STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.

Specifications

• Antigen: Phospho-Stat2 (Tyr690)
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Stat2
• Gene Accession No.: P52630
• Gene Alias: 1600010G07Rik; AW496480; BOS_5470; IMD44; interferon alpha induced transcriptional activator; ISGF-3; MGC59816; p113; Signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kDa; STAT; STAT 2; STAT113; STAT2; STAT-2
• Gene Symbols: Stat2
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human Stat2 around the phosphorylation site of Tyr690.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6773
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG