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Invitrogen™ Phospho-STAT6 (Tyr641) Monoclonal Antibody (J.187.3)
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Catalog No. PIMA514920
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100 μL
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PIMA514920 100 μL
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Catalog No. PIMA514920 Supplier Invitrogen™ Supplier No. MA514920
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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with the corresponding phospho-tyrosine residues of other Stat proteins.

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-STAT6 (Tyr641)
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone J.187.3
Concentration 103 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
Gene STAT6
Gene Accession No. P42226
Gene Alias 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Gene Symbols STAT6
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding pTyr641 of human Stat6.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6778
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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