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Invitrogen™ Phospho-STAT6 (Tyr641) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110157

Catalog No. PIPA5110157


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Description

Description

Immunogen sequence: RGYVP.

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-STAT6 (Tyr641)
Polyclonal
Unconjugated
STAT6
12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Rabbit
Affinity Chromatography
RUO
20852, 362896, 6778
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Immunohistochemistry (Paraffin), Western Blot
0.49 mg/mL
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
P42226, P52633
STAT6
A synthetic phosphorylated peptide around Y641 of human STAT6 (NP_0031443).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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