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Invitrogen™ Phospho-Stat6 (Tyr641) Recombinant Rabbit Monoclonal Antibody (Stat6Y641-G12), PE, Invitrogen™
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Catalog No. PIMA536908
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PIMA536908 100 Tests
PIMA537225 10 Tests
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Catalog No. PIMA536908 Supplier Invitrogen™ Supplier No. MA536908
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Rabbit Recombinant Monoclonal Antibody

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.
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Specifications

Antigen Phospho-Stat6 (Tyr641)
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone Stat6Y641-G12
Conjugate PE
Formulation PBS with 0.20% BSA and 0.09% sodium azide
Gene STAT6
Gene Accession No. P42226, P52633
Gene Alias 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Gene Symbols STAT6
Host Species Rabbit
Immunogen A synthetic phospho-peptide corresponding to residues surrounding Tyr641 of human phospho Stat6.
Purification Method Protein A/G
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20852, 6778
Target Species Human, Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG κ
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