Phospho-Synapsin 1 (Ser605) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA538528

Catalog No. PIPA538528

Description

SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: Phospho-Synapsin 1 (Ser605)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SYN1
• Gene Alias: Brain protein 4.1, SYN-1, synapsin I
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20964, 24949, 6853
• Content And Storage: -20°C
• Form: Liquid

• Applications: Peptide ELISA, Immunofluorescence, Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P17600, O88935, P09951
• Gene Symbols: SYN1
• Immunogen: A synthetic phosphopeptide derived from human Synapsin1 around the phosphorylation site of Ser605 (Q-A-SP-Q-A)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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