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Invitrogen™ Phospho-Talin 1 (Ser425) Polyclonal Antibody
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Catalog No. PIPA5106212
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PIPA5106212 100 μL
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Catalog No. PIPA5106212 Supplier Invitrogen™ Supplier No. PA5106212
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of TALIN1 only when phosphorylated at Ser425.

Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-235 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Talin 1 (Ser425)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TLN1
Gene Accession No. P26039, Q9Y490
Gene Alias ILWEQ; KIAA1027; talin 1; talin-1; TLN; TLN1
Gene Symbols TLN1
Host Species Rabbit
Immunogen A synthesized peptide derived from human TLN1(Accession Q9Y490), corresponding to amino acid residues around phosphorylated Ser425.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21894, 7094
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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