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Invitrogen™ Phospho-TAOK2 (Ser181) Polyclonal Antibody
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Catalog No. PIPA5114650
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PIPA5114650 100 μL
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Catalog No. PIPA5114650 Supplier Invitrogen™ Supplier No. PA5114650
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of TAO2 only when phosphorylated at Ser181.

TAOK2 (TAO1) is a serine/threonine kinase that may be an important regulator of the stress-responsive p38 MAP kinase pathway. In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEK ) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonist to the stress -responsive p38 MAPK (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-TAOK2 (Ser181)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene TAOK2
Gene Accession No. Q6ZQ29, Q9JLS3, Q9UL54
Gene Alias 1110033K02Rik; B230344N16; hKFC-C; Kiaa0881; Kinase from chicken homolog C; MAP3K17; mKIAA0881; prostate derived STE20-like kinase PSK; prostate-derived STE20-like kinase 1; prostate-derived sterile 20-like kinase 1; PSK; PSK1; PSK-1; PSK1-BETA; serine/threonine protein kinase TAO2; serine/threonine-protein kinase TAO2; serine-threonine kinase; tao; TAO kinase 2; TAO kinase 2TAO kinase 2; TAO1; TAO2; TAOK2; Thousand and one amino acid protein 2; thousand and one amino acid protein kinase 2; UNQ2971/PRO7431
Gene Symbols TAOK2
Host Species Rabbit
Immunogen A synthesized peptide derived from human TAO2 around the phosphorylation site of Ser181.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 381921, 64666, 9344
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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