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Invitrogen™ Phospho-TCF3 (Thr355) Polyclonal Antibody
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Catalog No. PIPA537753
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PIPA537753 100 μL
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Catalog No. PIPA537753 Supplier Invitrogen™ Supplier No. PA537753
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Description

Rabbit Polyclonal Antibody

A suggested positive control for IHC is human brain tissue.

TCF3 (E2A) is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-TCF3 (Thr355)
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TCF3
Gene Accession No. P15806, P15923, P21677
Gene Alias A1; AA408400; AGM8; Alf2; AW209082; bHLHb21; class B basic helix-loop-helix protein 21; E12; E12/E47; E2A; E47; helix-loop-helix protein HE47; immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin transcription factor 1; ITF1; Kappa-E2-binding factor; Me2; MGC129647; MGC129648; negative vitamin D response element-binding protein; NOL1-TCF3 fusion; Pan; Pan1; Pan2; pancreas specific transcription factor 1c; Ptf1c; TCF3; TCF-3; Tcfe2a; Transcription factor 3; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); transcription factor 3 variant 3; transcription factor A1; transcription factor E2a; Transcription factor E2-alpha; transcription factor ITF-1; Transcription regulator Pan; VDIR; VDR interacting repressor; vitamin D receptor-interacting repressor
Gene Symbols TCF3
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of threonine 355 (P-S-T(p)-P-V) derived from Human E2A.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171046, 21423, 6929
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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