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Invitrogen™ Phospho-TEK (Tyr1102) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA538394

Catalog No. PIPA538394


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Description

Description

Phospho-TEK (Tyr1102) Polyclonal Antibody for IHC (P), pep-ELISA

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells. TEK signaling appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis, and defects in TEK are associated with inherited venous malformations. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Immunoblotting showed that TIE2 expression was increased by thyroid-stimulating hormone and agents that increased intracellular cAMP. HSCs expressing the receptor tyrosine kinase TIE2 are quiescent and antiapoptotic and comprise a side population of HSCs that adhere to osteoblasts in the bone marrow niche.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-TEK (Tyr1102)
Polyclonal
Unconjugated
TEK
AA517024; Angiopoietin-1 receptor; CD202B; CD202b antigen; EC 2.7.10; EC 2.7.10.1; Endothelial tyrosine kinase; endothelial-specific receptor tyrosine kinase; endothelium-specific receptor tyrosine kinase 2; endothelium-specific receptor tyrosine kinase Tie-2; hTIE2; Hyk; mTIE2; p140 TEK; protein-tyrosine kinase Tie2; STK1; Tek; TEK receptor tyrosine kinase; TEK tyrosine kinase, endothelial; TEKT1; Tektin-1; Tie2; tie-2; tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; tyrosine kinases that contain immunoglobulin-like loops and epidermal growth factor-similar domains 2; tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor Tie-2; VMCM; VMCM1
Rabbit
Antigen Affinity Chromatography
RUO
21687, 7010
-20°C
Liquid
Immunohistochemistry (Paraffin), Peptide ELISA
1 mg/mL
Dulbecco's PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q02763, Q02858
TEK
A synthetic phosphopeptide derived from human TIE2 around the phosphorylation site of Tyr1102 (K-T-YP-V-N).
100 μg
Primary
Human, Mouse
Antibody
IgG
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