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Invitrogen™ Phospho-TEM8 (Tyr382) Polyclonal Antibody
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Catalog No. PIPA512976
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400 μL
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Catalog No. Quantity
PIPA512976 400 μL
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Catalog No. PIPA512976 Supplier Invitrogen™ Supplier No. PA512976
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with mouse and rat based on sequence homology.

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-TEM8 (Tyr382)
Applications Dot Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene ANTXR1
Gene Accession No. Q9H6X2
Gene Alias 2310008J16Rik; 2810405N18Rik; anthrax toxin receptor; anthrax toxin receptor 1; Antrx1; ANTXR1; ATR; FLJ10601; FLJ11298; FLJ21776; GAPO; TEM8; Tem-8; tumor endothelial marker 8
Gene Symbols ANTXR1
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y382 of human ANTXR1.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84168
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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