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Invitrogen™ Phospho-TFEB (Ser211) Polyclonal Antibody
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Catalog No. PIPA5114662
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PIPA5114662 100 μL
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Catalog No. PIPA5114662 Supplier Invitrogen™ Supplier No. PA5114662
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of TFEB only when phosphorylated at Ser211.

The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1. Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-TFEB (Ser211)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TFEB
Gene Accession No. P19484, Q9R210
Gene Alias Alpha TCFEB; ALPHATFEB; BHLHE35; Class E basic helix-loop-helix protein 35; RP4-696P19.3; T-cell transcription factor EB; Tcfeb; Tfeb; Transcription factor EB
Gene Symbols TFEB
Host Species Rabbit
Immunogen A synthesized peptide derived from human TFEB around the phosphorylation site of Ser211.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21425, 316214, 7942
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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