Invitrogen™ Phospho-TOP2A (Ser1525) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540274

Catalog No. PA540274

Description

This antibody is predicted to react with mouse and rat based on sequence homology.

Topo II alpha plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2 and M-phases in transformed and developmentally regulated normal cellsTopo II alpha is also implicated in drug resistance of tumor cells.

Specifications

• Antigen: Phospho-TOP2A (Ser1525)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TOP2A
• Gene Alias: DNA gyrase; DNA topoisomerase (ATP-hydrolyzing); DNA topoisomerase 2-alpha; DNA topoisomerase 2-alpha-like protein; DNA Topoisomerase II alpha; DNA topoisomerase II, 170 kD; DNA topoisomerase II, alpha isozyme; EC 5.99.1.3; OTTHUMP00000207108; P11388-1; TOP2; Top-2; Top2a; TOPOII; topoisomerase (DNA) 2 alpha; topoisomerase (DNA) II alpha; topoisomerase (DNA) II alpha 170kDa; topoisomerase ii alpha; topoisomersae II; TP2A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21973, 360243, 7153
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P11388, P41516, Q01320
• Gene Symbols: TOP2A
• Immunogen: Synthesized peptide derived from human Topo IIalpha around the phosphorylation site of S1525.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG