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Phospho-Torc1 (Ser151) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985415
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50-198-5415 100 μL
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Catalog No. 50-198-5415 Supplier Bioss Supplier No. BS3453R
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Description

Rabbit Polyclonal Antibody

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.Acts as a coactivator, in the SIK/TORC signaling pathway,being active when dephosphorylated and acts independently of CREB1 ′Ser-133′ phosphorylation.Enhances the interaction of CREB1 with TAF4.Regulates the expression of specific CREB-activated genes such as the steroidogenic gene,StAR.Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses.May be required for dendritic growth of developing cortical neurons.

Specifications

Antigen Phospho-Torc1 (Ser151)
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CRTC1
Gene Accession No. Q6UUV9
Gene Alias AI413414; CREB regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; Crtc1; FLJ14027; KIAA0616; MECT 1; MECT1; mKIAA0616; mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; Mucoepidermoid carcinoma translocated protein 1 homolog; R74955; TORC1; TORC-1; transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein (CREB) 1; Transducer of regulated cAMP response element-binding protein 1; WAMTP1
Gene Symbols CRTC1
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human Torc1 around the phosphorylation site of Ser151.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23373
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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