Invitrogen™ H3K27me3S28ph Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 491015

Catalog No. 50-255-0804

Description

H3K27me3S28ph Polyclonal Antibody for Western Blot, ICC/IF, IP, ChIP, ELISA, DB

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.

Specifications

• Antigen: H3K27me3S28ph
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H3C15
• Gene Alias: H3; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3/l; H3/M; H3/n; H3/o; H3-143; H3-53; H3-614; H3b; H3-B; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F2; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; HIST1H3A; Hist1h3b; Hist1h3c; HIST1H3D; Hist1h3e; Hist1h3f; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3b; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; histone cluster 1, H3b; histone cluster 2, H3a; histone cluster 2, H3c; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone H3.1; Histone H3.2; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; histone H3/m; Histone H3/o; M32461
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ChIP Assay, Dot Blot, ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: Conc. Not Determined
• Formulation: Whole serum with <0.1% sodium azide
• Gene Accession No.: Q71DI3
• Gene Symbols: H3C15, H3C2
• Immunogen: Raised against histone H3 containing the trimethylated lysine 27 and the phosphorylated serine 28 (H3K27me3S28p), using a KLH conjugated synthetic peptide.
• Regulatory Status: RUO
• Gene ID (Entrez): 333932, 8358
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid