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Invitrogen™ Phospho-TrkA/TrkB (Tyr674, Tyr675, Tyr706, Tyr707) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5121285
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Description
Positive test controls include: HeLa. Immunogen sequence: TDYYRV.
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Specifications
Phospho-TrkA/TrkB (Tyr674, Tyr675, Tyr706, Tyr707) | |
Polyclonal | |
Unconjugated | |
NTRK1 | |
BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C80751; gp140trk; GP145-TrkB; GP145-TrkB/GP95-TrkB; high affinity nerve growth factor receptor; MTC; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 1; neurotrophic receptor tyrosine kinase 2; Neurotrophic tyrosine kinase receptor type 1; Neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 1; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK1; NTRK2; Oncogene TRK; p140-TrkA; RATTRKB1; Slow nerve growth factor receptor; Tkr; Tkrb; trk; TRK1; TRK1-transforming tyrosine kinase protein; Trka; trk-A; TrkA neurotrophin receptor; trkA proto-oncogene receptor; TRKB; Trk-B; TrkB tyrosine kinase; TRKB1; Tropomyosin-related kinase A; tropomyosin-related kinase B; Tyrosine kinase receptor; Tyrosine kinase receptor A; tyrosine kinase receptor B | |
Rabbit | |
Affinity Chromatography | |
RUO | |
4914, 4915 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
0.5 mg/mL | |
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
P04629, Q16620 | |
NTRK1, Ntrk2 | |
A synthetic phosphorylated peptide around Y674 & Y675 of human TrkANTRK1 (NP_0010123311). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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