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Phospho-TrkA (Tyr791, Tyr817) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
SDP

Catalog No. 501985614
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50-198-5614 100 μL
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Catalog No. 50-198-5614 Supplier Bioss Supplier No. BS3732R
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Description

Rabbit Polyclonal Antibody

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Specifications

Antigen Phospho-TrkA (Tyr791, Tyr817)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NTRK1
Gene Accession No. P04629, P15209, P35739, Q16620, Q3UFB7, Q63604
Gene Alias BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C80751; gp140trk; GP145-TrkB; GP145-TrkB/GP95-TrkB; High affinity nerve growth factor receptor; MTC; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 1; neurotrophic receptor tyrosine kinase 2; Neurotrophic tyrosine kinase receptor type 1; Neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 1; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; Ntrk1; NTRK2; Oncogene TRK; p140-TrkA; RATTRKB1; Slow nerve growth factor receptor; Tkr; Tkrb; Trk; TRK1; TRK1-transforming tyrosine kinase protein; Trka; Trk-A; TrkA neurotrophin receptor; trkA proto-oncogene receptor; TRKB; Trk-B; TrkB tyrosine kinase; TRKB1; Tropomyosin-related kinase A; Tropomyosin-related kinase B; Tyrosine kinase receptor; Tyrosine kinase receptor A; tyrosine kinase receptor B
Gene Symbols NTRK1, Ntrk2
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human TrkA Tyr791+TrkB Tyr817.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18211, 18212, 25054, 4914, 4915, 59109
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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