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Invitrogen™ Phospho-TrkC (Tyr705) Polyclonal Antibody
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Catalog No. PIPA599562
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100 μL
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PIPA599562 100 μL
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Catalog No. PIPA599562 Supplier Invitrogen™ Supplier No. PA599562
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of TrkC only when phosphorylated at Tyr705.

NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-TrkC (Tyr705)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Ntrk3
Gene Accession No. Q03351, Q16288, Q6VNS1
Gene Alias AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C
Gene Symbols Ntrk3
Host Species Rabbit
Immunogen A synthesized peptide derived from human NTRK3(Accession Q16288), corresponding to amino acid residues around phosphorylated Tyr705.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18213, 29613, 4916
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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