Phospho-Tyk2 (Tyr1054, Tyr1055) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS3437R

Catalog No. 50-198-5399

Description

TYK2 is a member of the Janus kinases (JAKs) protein family. TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits and is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Specifications

• Antigen: Phospho-Tyk2 (Tyr1054, Tyr1055)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TYK2
• Gene Alias: 4833430L21Rik; AW540162; BRE1; BRE1A; C79397; hBRE1; IMD35; JTK1; mKIAA4116; Non-receptor tyrosine-protein kinase TYK2; Tyk2; tyrosine kinase 2; tyrosine kinase TYK2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100361294, 54721, 7297
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P29597, Q9R117
• Gene Symbols: TYK2
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human Tyk2 around the phosphorylation site of Tyr1054/1055.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG