Invitrogen™ Phospho-UBA52 (Ser65) Polyclonal Antibody

Catalog No.	Quantity
PIPA5114668	100 μL

Catalog No. PIPA5114668 Supplier Invitrogen™ Supplier No. PA5114668

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of ubiquitin only when phosphorylated at Ser65.

Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi.

Specifications

• Antigen: Phospho-UBA52 (Ser65)
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene: UBA52
• Gene Accession No.: P62984, P62986, P62987
• Gene Alias: 60S ribosomal protein L40; CEP52; D8Ertd21e; Gm1863; HUB L40; HUBCEP52; L40; Large ribosomal subunit protein eL40; MGC127041; RPL40; RPS27A; Uba52; UBB; Ubc; Ubcep2; Ubiquitin; Ubiquitin A-52 residue ribosomal protein fusion product 1; ubiquitin and ribosomal protein L40; ubiquitin carboxyl extension protein 52; ubiquitin/60S ribosomal fusion protein; ubiquitin-52 amino acid fusion protein; ubiquitin-60S ribosomal protein L40; ubiquitin-CEP52; Unknown (protein for MGC:127041)
• Gene Symbols: UBA52
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human UBA52 around the phosphorylation site of Ser65.
• Purification Method: sequential chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22186, 64156, 7311
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov