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Invitrogen™ Phospho-UBF-1 (Thr117) Polyclonal Antibody
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Catalog No. PIPA5105512
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PIPA5105512 100 μL
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Catalog No. PIPA5105512 Supplier Invitrogen™ Supplier No. PA5105512
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of UBF1 only when phosphorylated at Thr117.

UBF-1 encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.
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Specifications

Antigen Phospho-UBF-1 (Thr117)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene UBTF
Gene Accession No. P17480, P25976, P25977
Gene Alias 90-kDa nucleolus organizer region autoantigen; A930005G04Rik; Autoantigen NOR-90; NOR90; NOR-90; Nucleolar transcription factor 1; Tcfubf; transcription factor UBF; UBF; UBF1; UBF-1; UBF2; Ubtf; upstream binding transcription factor, RNA polymerase I; upstream-binding factor 1
Gene Symbols UBTF
Host Species Rabbit
Immunogen A synthesized peptide derived from human UBTF(Accession P17480), corresponding to amino acid residues around phosphorylated Thr117.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21429, 25574, 7343
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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