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Phospho-VAV1 (Tyr174) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986670
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50-198-6670 100 μL
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Catalog No. 50-198-6670 Supplier Bioss Supplier No. BS5594R
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Description

Rabbit Polyclonal Antibody

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Specifications

Antigen Phospho-VAV1 (Tyr174)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene VAV1
Gene Accession No. P15498
Gene Alias oncogene vav; p95; p95vav; Proto-oncogene vav; Vav; vav 1 guanine nucleotide exchange factor; vav 1 oncogene; vav guanine nucleotide exchange factor 1; vav oncogene; vav proto-oncogene; Vav1; vav-T
Gene Symbols VAV1
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human VAV1 around the phosphorylation site of Tyr174.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7409
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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