Phospho-VDR (Ser51) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA539757

Catalog No. PIPA539757

Description

Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

Specifications

• Antigen: Phospho-VDR (Ser51)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VDR
• Gene Alias: 1,25-dihydroxyvitamin D3 receptor, NR1I1, vitamin D receptor, vitamin D3 receptor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22337, 24873, 7421
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P11473, P48281, P13053
• Gene Symbols: VDR
• Immunogen: A synthetic phosphopeptide derived from human Vitamin D3 Receptor around the phosphorylation site of Ser51 (R-R-SP-M-K)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG