Invitrogen™ Phospho-VGAT (Ser462) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105326

Catalog No. PIPA5105326

Description

Antibody detects endogenous levels of SLC32A1 only when phosphorylated at Ser462.

The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles (McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).

Specifications

• Antigen: Phospho-VGAT (Ser462)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC32A1
• Gene Alias: GABA and glycine transporter; GVAT; hVIAAT; mVGAT; mVIAAT; R75019; rGVAT; SLC32A1; solute carrier family 32 (GABA vesicular transporter), member 1; solute carrier family 32 member 1; vasicular inhibitory amino acid transporter 10D; vesicular GABA transporter; Vesicular inhibitory amino acid transporter; Vgat; Viaat
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 140679, 22348, 83612
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O35458, O35633, Q9H598
• Gene Symbols: SLC32A1
• Immunogen: A synthesized peptide derived from human SLC32A1(Accession Q9H598), corresponding to amino acid residues around phosphorylated Ser462.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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