Invitrogen™ Phospho-WEE1 (Ser139) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105559

Catalog No. PIPA5105559

Description

Antibody detects endogenous levels of WEE1 only when phosphorylated at Ser139.

WEE1, which is classified as a Ser/Thr kinase by sequence analysis, has been shown to inactivate multiple CDKs by tyrosine phosphorylation. Wee1 protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

Specifications

• Antigen: Phospho-WEE1 (Ser139)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WEE1
• Gene Alias: CTRCT30; DKFZp686I18166; epididymis luminal protein 113; fa20h03; FLJ16446; HEL113; VIM; Vimentin; wee 1 homolog; WEE 1 homolog 1 (S. pombe); Wee1; WEE1 G2 checkpoint kinase; WEE1 homolog; wee1 protein; WEE1 tyrosine kinase; WEE1+ homolog; Wee1A; wee1A kinase; WEE1hu; wee1-like protein kinase; wu:fa20h03; zgc:136514
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22390, 308937, 7465
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P30291, P47810, Q63802
• Gene Symbols: WEE1
• Immunogen: A synthesized peptide derived from human WEE1(Accession P30291), corresponding to amino acid residues around phosphorylated Ser139.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG