Invitrogen™ Phospho-WNK4 (Ser575) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5114673

Catalog No. PIPA5114673

Description

Antibody detects endogenous levels of WNK4 only when phosphorylated at Ser575.

This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.

Specifications

• Antigen: Phospho-WNK4 (Ser575)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Wnk4
• Gene Alias: 2010002J11Rik; Ac2-059; Pha2b; Prkwnk4; protein kinase lysine-deficient 4; Protein kinase with no lysine 4; protein kinase, lysine deficient 4; protein kinase, lysine-deficient 4; RP23-281C18.8; serine/threonine-protein kinase WNK4; WNK lysine deficient protein kinase 4; WNK4; WNK4 Ser/Thr kinase
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 287715, 65266, 69847
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q7TPK6, Q80UE6, Q96J92
• Gene Symbols: Wnk4
• Immunogen: A synthesized peptide derived from human WNK4 around the phosphorylation site of Ser575.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG