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Phospho-XRCC1 (Ser485, Thr488) Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501557162
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50-155-7162 100 μL
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Catalog No. 50-155-7162 Supplier Bethyl Laboratories, Inc Supplier No. A300231A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Rat

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.

Specifications

Antigen Phospho-XRCC1 (Ser485,Thr488)
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene XRCC1
Gene Accession No. P18887, Q60596
Gene Alias RCC
Gene Symbols XRCC1
Host Species Rabbit
Immunogen Surrounding serine 485 and threonine 488
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22594, 7515
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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