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Phospho-XRCC1 (Ser518, Thr519, Thr523) Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc IHC00115
Description
The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.Specifications
| Phospho-XRCC1 (Ser518,Thr519,Thr523) | |
| Polyclonal | |
| TBS with 0.1% BSA and 0.09% sodium azide | |
| P18887, Q60596 | |
| Xrcc1 | |
| Surrounding serine 518 and threonine 519/523 | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| Immunofluorescence, Immunohistochemistry | |
| Unconjugated | |
| XRCC1 | |
| RCC | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 22594, 7515 | |
| 4° C | |
| Liquid |
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