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Invitrogen™ Phospho-YBX1 (Ser176) Polyclonal Antibody
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Catalog No. PIPA5105600
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100 μL
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PIPA5105600 100 μL
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Catalog No. PIPA5105600 Supplier Invitrogen™ Supplier No. PA5105600
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of YB1 only when phosphorylated at Ser176.

YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-YBX1 (Ser176)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene YBX1
Gene Accession No. P62960, P62961, P67809
Gene Alias 1700102N10Rik; BP8; BP-8; Byb1; C79409; Cbfa; CBF-A; CCAAT-binding; CCAAT-binding transcription factor 1 subunit A; CCAAT-binding transcription factor I subunit A; CSDA2; CSDB; dbpB; DNA binding protein B; DNA-binding protein B; EF1A; EFI-A; enhancer factor 1 alpha; enhancer factor 1 subunit A; enhancer factor I subunit A; major histocompatibility complex, class II, Y box-binding protein I; MDR NF1; MDR-NF1; MGC104858; MGC110976; MGC117250; Msy1; Msy-1; mYB-1a; Nsep1; NSEP-1; nuclease sensitive element binding protein 1; nuclease-sensitive element-binding protein 1; Y box binding protein 1; Y box protein 1; Y box transcription factor; YB1; YB-1; Y-box binding protein 1; Y-box transcription factor; Y-box-binding protein 1; YBX1
Gene Symbols YBX1
Host Species Rabbit
Immunogen A synthesized peptide derived from human YBX1(Accession P67809), corresponding to amino acid residues around phosphorylated Ser176.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22608, 4904, 500538
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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