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Phospho-ZNF598 (Tyr306) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982049
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50-198-2049 100 μL
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Catalog No. 50-198-2049 Supplier Bioss Supplier No. BS12222R
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Description

Rabbit Polyclonal Antibody

ZNF598 (E3 ubiquitin-protein ligase ZNF598) plays a key role in the ribosome quality control (RQC). RQC is a pathway that takes place when a ribosome has stalled during translation. It is required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40A ribosomal protein RPS10/eS10 and RPS3/uS3. Stalling precludes synthesis of a long poly-lysine tail and initiated the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide.

Specifications

Antigen Phospho-ZNF598 (Tyr306)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ZNF598
Gene Accession No. Q86UK7
Gene Alias BC023040; C6orf149; E3 ubiquitin-protein ligase ZNF598; FLJ00086; ISD11; Ntrap; Zfp598; Zinc finger protein 598; Znf598
Gene Symbols ZNF598
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human ZNF598 around the phosphorylation site of Tyr306.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 90850
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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