Phospho-Zyxin (Ser142, Ser143) Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-5539	100 μL

Catalog No. 50-198-5539 Supplier Bioss Supplier No. BS3620R

Description

Rabbit Polyclonal Antibody

Zyxin is involved in focal adhesions, which are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

Specifications

• Antigen: Phospho-Zyxin (Ser142, Ser143)
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: ZYX
• Gene Accession No.: Q15942
• Gene Alias: 9530098H06Rik; BOS_4797; ESP-2; HED-2; R75157; Zyx; Zyxin; Zyxin-2
• Gene Symbols: ZYX
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human Zyxin around the phosphorylation site of Ser142/Ser143.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7791
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG