Invitrogen™ Phospholamban Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA519351

Catalog No. PIPA519351

Description

This antibody is predicted to react with bovine and porcine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.

Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.

Specifications

• Antigen: Phospholamban
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLN
• Gene Alias: cardiac CMH18; Cardiac phospholamban; CMD1P; CMH18; phospholamban; Plb; Plm; PLN; unnamed protein product
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 5350, 64672
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P26678, P61016
• Gene Symbols: PLN
• Immunogen: Synthetic peptide sequence (KVQYLTRSAIRR) corresponding to the N-terminus amino acids of Phospholamban (aa 3-14).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov