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Tocris Bioscience™ PI 103 hydrochloride
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Catalog No. 29301
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29-301 1 mg
29-301-0 10 mg
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Catalog No. 29-301 Supplier Tocris Bioscience™ Supplier No. 2930/1
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Description

Inhibitor of PI 3-kinase, mTOR and DNA-PK

Inhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR (IC50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ∽ 1000 and 2300 nM for DNA-PK, p110α, mTORC1, PI 3-KC2β, p110δ, mTORC2, p110β, p110γ, ATR, ATM, PI 3-KC2α and hsVPS34 respectively). Inhibits growth of human tumor xenografts in mice in vivo. Induces autophagosome formation in glioma cells.

Chemical Identifiers

CAS 371935-79-4
Molecular Formula C19H17ClN4O3

Specifications

Quantity 1 mg
Formula Weight 384.82
Purity >98%
Molecular Weight (g/mol) 384.82
Chemical Name or Material PI 103 hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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