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  7. PI 103 hydrochloride, Tocris Bioscience™ 

PI 103 hydrochloride, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
1mg
10mg
50mg
This item is not returnable. View return policy
371935-79-4
C19H17ClN4O3
384.82
XSQMYBFFYPTMFE-UHFFFAOYSA-N
pi 103 hydrochloride,pi-103 hydrochloride,pi-103 hydrochloride,pi103 hydrochloride,pubchem22442,pi-103, hydrochloride,c19h16n4o3.clh,pi 103 hydrochloride;pi103 hydrochloride,3-4-morpholinopyrido 3',2':4,5 furo 3,2-d pyrimidin-2-yl phenol hydrochloride,3-4-4-morpholinylpyrido 3',2':4,5 f uro 3,2-d pyrimidin-2-yl phenol hydrochloride
16739368
3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol;hydrochloride
C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O.Cl
This item is not returnable. View return policy
371935-79-4
C19H17ClN4O3
384.82
XSQMYBFFYPTMFE-UHFFFAOYSA-N
pi 103 hydrochloride,pi-103 hydrochloride,pi-103 hydrochloride,pi103 hydrochloride,pubchem22442,pi-103, hydrochloride,c19h16n4o3.clh,pi 103 hydrochloride;pi103 hydrochloride,3-4-morpholinopyrido 3',2':4,5 furo 3,2-d pyrimidin-2-yl phenol hydrochloride,3-4-4-morpholinylpyrido 3',2':4,5 f uro 3,2-d pyrimidin-2-yl phenol hydrochloride
16739368
3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol;hydrochloride
C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O.Cl

Description

Inhibitor of PI 3-kinase, mTOR and DNA-PK

Inhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR (IC 50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ∽ 1000 and 2300 nM for DNA-PK, p110α, mTORC1, PI 3-KC2β, p110δ, mTORC2, p110β, p110γ, ATR, ATM, PI 3-KC2α and hsVPS34 respectively). Inhibits growth of human tumor xenografts in mice in vivo. Induces autophagosome formation in glioma cells.

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Quantity 1mg
Formula Weight 384.82
Percent Purity >98%
Chemical Name or Material PI 103 hydrochloride

Safety and Handling

Recommended Storage : Desiccate at +4°C