Invitrogen™ PI16 Monoclonal Antibody (5D4C7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA548813

Catalog No. FERMA548813

Description

PI16 Monoclonal Antibody for Western Blot, Flow, ELISA

The PI16 gene encodes the protein peptidase inhibitor 16, which is a member of the protease inhibitor family and plays roles in modulating protease activity within tissues. PI16 is primarily expressed in the prostate but is also found in other tissues, where it contributes to extracellular matrix organization and integrity by inhibiting serine proteases. By regulating protease activity, PI16 helps maintain tissue homeostasis and influences processes such as cell proliferation, differentiation, and migration. This protein's function is significant in preventing excessive proteolytic activity that could lead to tissue damage or contribute to pathological conditions like inflammation and cancer. Specifically, PI16's role in the prostate gland has been associated with modulating growth and repair mechanisms, providing potential implications in prostate cancer progression where protease activity is often dysregulated. Current research focuses on understanding PI16's interactions and regulatory mechanisms to explore its therapeutic potential in diseases characterized by abnormal protease activities.

Specifications

• Antigen: PI16
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q6UXB8
• Gene Symbols: PI16
• Immunogen: Purified recombinant fragment of human CD364 (AA: 79-210) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 5D4C7
• Conjugate: Unconjugated
• Gene: PI16
• Gene Alias: 1200009H11Rik; CD364; Cripi; CRISP9; CRISP-9; Cysteine-rich protease inhibitor; cysteine-rich secretory protein 9; microseminoprotein, beta-binding protein; MSMBBP; peptidase inhibitor 16; Pi16; PI-16; protease inhibitor 16; PSEC0164; PSP94-binding protein; PSPBP; UNQ289/PRO328
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 221476
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid