PI3 Kinase p55 gamma Polyclonal Antibody, Rockland™

Goat Polyclonal Antibody

Supplier:  Rockland Immunochemicals 600101ML2

Catalog No. 50-199-1585

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This affinity purified antibody is directed against human PI 3 Kinase p55 gamma. A BLAST analysis was used to suggest cross-reactivity with the antigen based on 100% homology with the immunizing sequence to mouse and rat, 94.1% homology to bovine.

PIK3R3 binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. It is a component of a heterodimer of p110 (catalytic) and p55 (regulatory) subunits. The protein is expressed at highest levels in brain and testis. Lower levels are detected in adipose tissue, kidney, heart, lung and skeletal muscle. The protein contains 2 SH2 domains.

Specifications

• Antigen: PI3 Kinase p55 gamma
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pik3r3
• Gene Alias: AA414954; p55; p55-GAMMA; p55PIK; phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55); Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; phosphatidylinositol 3-kinase p55 subunit; Phosphatidylinositol 3-kinase regulatory subunit gamma; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma); phosphoinositide-3-kinase regulatory subunit 3; phosphoinositide-3-kinase, regulatory subunit 3 (gamma); PI3K regulatory subunit gamma; PI3-kinase p85 subunit gamma; PI3-kinase regulatory subunit gamma; PI3-kinase subunit p55-gamma; Pik3r3; ptdIns-3-kinase p85-gamma; ptdIns-3-kinase regulatory subunit gamma; ptdIns-3-kinase regulatory subunit p55-gamma; RP4-533D7.2
• Host Species: Goat
• Regulatory Status: RUO
• Gene ID (Entrez): 18710, 8503
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Concentration: 1.02 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: Q64143, Q92569
• Gene Symbols: Pik3r3
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody