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PI3 Kinase p55 gamma Polyclonal Antibody, Rockland™
SDP

Goat Polyclonal Antibody

Supplier:  Rockland Immunochemicals 600101ML2

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Catalog No. 50-199-1585


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Description

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This affinity purified antibody is directed against human PI 3 Kinase p55 gamma. A BLAST analysis was used to suggest cross-reactivity with the antigen based on 100% homology with the immunizing sequence to mouse and rat, 94.1% homology to bovine.

PIK3R3 binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. It is a component of a heterodimer of p110 (catalytic) and p55 (regulatory) subunits. The protein is expressed at highest levels in brain and testis. Lower levels are detected in adipose tissue, kidney, heart, lung and skeletal muscle. The protein contains 2 SH2 domains.
Specifications

Specifications

PI3 Kinase p55 gamma
Polyclonal
Unconjugated
Pik3r3
AA414954; p55; p55-GAMMA; p55PIK; phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55); Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; phosphatidylinositol 3-kinase p55 subunit; Phosphatidylinositol 3-kinase regulatory subunit gamma; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma); phosphoinositide-3-kinase regulatory subunit 3; phosphoinositide-3-kinase, regulatory subunit 3 (gamma); PI3K regulatory subunit gamma; PI3-kinase p85 subunit gamma; PI3-kinase regulatory subunit gamma; PI3-kinase subunit p55-gamma; Pik3r3; ptdIns-3-kinase p85-gamma; ptdIns-3-kinase regulatory subunit gamma; ptdIns-3-kinase regulatory subunit p55-gamma; RP4-533D7.2
Goat
RUO
18710, 8503
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
1.02 mg/mL
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Q64143, Q92569
Pik3r3
100 μg
Primary
Human, Mouse
Antibody
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