Invitrogen™ PIAS1/PIAS2 Recombinant Rabbit Monoclonal Antibody (8P1D2)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538199

Catalog No. PIMA538199

Description

Positive Samples: HepG2, Mouse brain Immunogen sequence: DNQHYNTSLL AAAAAAVSDD QDLLHSSRFF PYTSSQMFLD QLSAGGSTSL PTTNGSSSGS NSSLVSSNSL RESHSHTVTN RSSTDTASIF GIIPDIISLD.

This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].

Specifications

• Antigen: PIAS1/PIAS2
• Classification: Recombinant Monoclonal
• Concentration: 0.4 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O75925, O75928, O88907, Q6AZ28, Q8C5D8
• Gene Symbols: PIAS1, PIAS2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 552-651 of human PIAS1+PIAS2 (O75925).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 8P1D2
• Conjugate: Unconjugated
• Gene: PIAS1
• Gene Alias: 2900068C24Rik; 6330408K17Rik; AI462206; androgen receptor-interacting protein 3; AR interacting protein; ARIP3; AU018068; DAB2-interacting protein; Ddxbp1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; Dib; DIP; E3 SUMO-protein ligase PIAS1; E3 SUMO-protein ligase PIAS2; E3 SUMO-protein transferase PIAS1; E3 SUMO-protein transferase PIAS2; GBP; GU/RH-II; Gu-binding protein; MIZ; Miz1; msx-interacting zinc finger protein; Msx-interacting-zinc finger; msx-interacting-zinc finger protein; PIAS1; Pias2; PIAS-NY protein; PIASX; PIASxalpha; PIASX-ALPHA; PIASxalpha6; PIASxb; PIASxbeta; PIASX-BETA; protein inhibitor of activated STAT 1; protein inhibitor of activated STAT 2; protein inhibitor of activated STAT protein 1; Protein inhibitor of activated STAT x; protein inhibitor of activated STAT, 1; protein inhibitor of activated STAT, 2; protein inhibitor of activated STAT-1; Protein inhibitor of activated STAT2; RING-type E3 ubiquitin transferase PIAS1; RING-type E3 ubiquitin transferase PIAS2; RNA helicase II-binding protein; SIZ2; zinc finger, MIZ-type containing 3; zinc finger, MIZ-type containing 4; ZMIZ3; ZMIZ4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17344, 300772, 56469, 83422, 8554, 9063
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov