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PIAS1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501734068 Shop All Proteintech Group Inc Products
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50-173-4068 150 μL
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Catalog No. 50-173-4068 Supplier Proteintech Group Inc Supplier No. 233951AP150UL
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Description

Rabbit Polyclonal Antibody

PIAS1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in androgen receptor initiation and maintece of spermatogenesis. The effects of transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.

Specifications

Antigen PIAS1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.49 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PIAS1
Gene Accession No. O75925
Gene Alias DDXBP1, DEAD/H box binding protein 1, E3 SUMO protein ligase PIAS1, Gu binding protein, GU/RH II, PIAS1, ZMIZ3
Gene Symbols PIAS1
Host Species Rabbit
Immunogen PIAS1 Fusion Protein Ag18132
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8554
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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