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PIAS1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 233951AP150UL

Encompass_Preferred

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Catalog No. 50-173-4068


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Description

Description

PIAS1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in androgen receptor initiation and maintece of spermatogenesis. The effects of transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.
Specifications

Specifications

PIAS1
Polyclonal
Unconjugated
PIAS1
DDXBP1, DEAD/H box binding protein 1, E3 SUMO protein ligase PIAS1, Gu binding protein, GU/RH II, PIAS1, ZMIZ3
Rabbit
Antigen Affinity Chromatography
RUO
8554
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.49 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O75925
PIAS1
PIAS1 Fusion Protein Ag18132
150 μL
Primary
Human
Antibody
IgG
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