Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Pifithrin-α hydrobromide, Tocris Bioscience™
Click to view available options
Quantity:
10 mg
50 mg
Description
Inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of cancer therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM). Cyclic analog available (Cat. No. 3843).
Specifications
Quantity | 50 mg |
Formula Weight | 367.3 |
Percent Purity | >98% |
Chemical Name or Material | Pifithrin-α hydrobromide |
Safety and Handling
Recommended Storage : Desiccate at -20°C