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  8. Pifithrin-α hydrobromide, Tocris Bioscience™

Pifithrin-α hydrobromide, Tocris Bioscience™

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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
63208-82-2
C16H19BrN2OS
367.305
HAGVCKULCLQGRF-UHFFFAOYSA-N
pifithrin-alpha, pft-alpha, pifithrin, pifithrin-alpha hydrobromide, unii-d213b92s1y, pifithrin-, a pft, a, 2-2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl-1-p-tolylethanone hydrobromide, 2-2-imino-4,5,6,7-tetrahydrobenzo d thiazol-3 2h-yl-1-p-tolylethanone hydrobromide, 2-2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl-1-p-tolylethanone, hbr, pifithrin-alpha mi
9929138
2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone;hydrobromide
CC1=CC=C(C=C1)C(=O)CN2C3=C(CCCC3)SC2=N.Br
This item is not returnable. View return policy
63208-82-2
C16H19BrN2OS
367.305
HAGVCKULCLQGRF-UHFFFAOYSA-N
pifithrin-alpha, pft-alpha, pifithrin, pifithrin-alpha hydrobromide, unii-d213b92s1y, pifithrin-, a pft, a, 2-2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl-1-p-tolylethanone hydrobromide, 2-2-imino-4,5,6,7-tetrahydrobenzo d thiazol-3 2h-yl-1-p-tolylethanone hydrobromide, 2-2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl-1-p-tolylethanone, hbr, pifithrin-alpha mi
9929138
2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone;hydrobromide
CC1=CC=C(C=C1)C(=O)CN2C3=C(CCCC3)SC2=N.Br

Description

p53 inhibitor. Also aryl hydrocarbon receptor agonist

Inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of cancer therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM). Cyclic analog available (Cat. No. 3843).
Quantity 50 mg
Formula Weight 367.3
Percent Purity >98%
Chemical Name or Material Pifithrin-α hydrobromide

Safety and Handling

Recommended Storage : Desiccate at -20°C