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Tocris Bioscience™ Pifithrin-α hydrobromide

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Quantity:
10 mg
50 mg
Description
Inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of cancer therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM). Cyclic analog available (Cat. No. 3843).
Specifications
Specifications
Quantity | 50 mg |
Formula Weight | 367.3 |
Purity | >98% |
Molecular Weight (g/mol) | 367.305 |
Chemical Name or Material | Pifithrin-α hydrobromide |
Safety and Handling
Recommended Storage | Desiccate at -20°C |
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