Invitrogen™ PIGA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551527

Catalog No. PIPA551527

Description

Immunogen sequence: FADVSSVLTN KLLTVSLCDT NHIICVSYTS KENTVLRAAL NPEIVSVIPN AVDPTDFTPD PFRRHDSITI VVVSRLVYRK GIDLLSGIIP ELCQKYPDLN FIIGGEGPKR II Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized.

Specifications

• Antigen: PIGA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PIGA
• Gene Alias: AI194334; class A GlcNAc-inositol phospholipid assembly protein; GLCNAC-PI synthesis protein; GPI anchor biosynthesis; GPI3; MCAHS2; N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein; phosphatidylinositol glycan anchor biosynthesis class A; phosphatidylinositol glycan anchor biosynthesis, class A; phosphatidylinositol glycan anchor biosynthesis, class A (paroxysmal nocturnal hemoglobinuria); phosphatidylinositol glycan, class A; phosphatidylinositol N-acetylglucosaminyltransferase subunit A; Phosphatidylinositol-glycan biosynthesis class A protein; phosphatidylinositol-glycan biosynthesis, class A protein; phosphatidylinositolglycan class A; PIGA; PIG-A; PNH1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5277
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P37287
• Gene Symbols: PIGA
• Immunogen: Recombinant protein corresponding to Human PIGA. Recombinant protein control fragment (Product #RP-91907).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov