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Invitrogen™ PIGA Polyclonal Antibody
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Catalog No. PIPA5104006
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100 μL
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PIPA5104006 100 μL
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Catalog No. PIPA5104006 Supplier Invitrogen™ Supplier No. PA5104006
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PIGA.

This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIGA
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PIGA
Gene Accession No. P37287, Q64323
Gene Alias AI194334; class A GlcNAc-inositol phospholipid assembly protein; GLCNAC-PI synthesis protein; GPI anchor biosynthesis; GPI3; MCAHS2; N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein; phosphatidylinositol glycan anchor biosynthesis class A; phosphatidylinositol glycan anchor biosynthesis, class A; phosphatidylinositol glycan anchor biosynthesis, class A (paroxysmal nocturnal hemoglobinuria); phosphatidylinositol glycan, class A; phosphatidylinositol N-acetylglucosaminyltransferase subunit A; Phosphatidylinositol-glycan biosynthesis class A protein; phosphatidylinositol-glycan biosynthesis, class A protein; phosphatidylinositolglycan class A; PIGA; PIG-A; PNH1
Gene Symbols PIGA
Host Species Rabbit
Immunogen A synthesized peptide derived from human PIGA(Accession P37287), corresponding to amino acid residues T446-R484.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18700, 363464, 5277
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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