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Invitrogen™ PIGF Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575899

Catalog No. PIPA575899


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Description

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Phosphatidylinositol-glycans(PIGs) aremulti-passtransmembrane proteins that localize to the endoplasmicreticulum. PIGs exhibitvariousfunctions but all are crucial for the biosynthesis of the glycosylphosphatidylinositol (GPI) anchor. Some PIG proteins are components of the GPI transamidase complex and play a role in the recognition of either the GPI attachmentsignal or the lipid portion of GPI. Other PIGs belong to the glycosyltransferase complex and function in the transfer of N-acetylglucosamine (GlcNAc) to phosphatidyli nositol (PI). A variety of other PIGs play distinct rolesin GPIsynthesis. PIG-F functions as an auxiliary subunit of ethanolamine phosphate (EtNP) transferases. It associates with PIG-O and isrequired for its expression and stability. Together these two PIGs function as an EtNP transferase and catalyze the transfer of EtNP to the third mannose (Man-3) of GPI. Amutation in the gene encoding PIG-F may result in a block of EtNP addition to Man-3 and lead to an absence of GPI-anchored proteins.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PIGF
Polyclonal
Unconjugated
PIGF
GPI11 homolog; phosphatidylinositol glycan anchor biosynthesis class F; phosphatidylinositol glycan anchor biosynthesis, class F; phosphatidylinositol glycan, class F; phosphatidylinositol-glycan biosynthesis class F protein; phosphatidylinositol-glycan biosynthesis class protein-like protein; PIGF; PIG-F; Unknown (protein for MGC:133893)
Rabbit
Antigen affinity chromatography
RUO
18701, 5281, 681086
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
1 mg/mL
PBS with 0.05% sodium azide; pH 7.3
O09101, Q07326
PIGF
Synthetic peptide corresponding to residues in Human PIGF.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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