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Invitrogen™ PIGF Polyclonal Antibody
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Catalog No. PIPA562396
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100 μL
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PIPA562396 100 μL
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Catalog No. PIPA562396 Supplier Invitrogen™ Supplier No. PA562396
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GPNLKAWLRV FSRNGVTSIW EN Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 95%.

Phosphatidylinositol-glycans(PIGs) aremulti-passtransmembrane proteins that localize to the endoplasmicreticulum. PIGs exhibitvariousfunctions but all are crucial for the biosynthesis of the glycosylphosphatidylinositol (GPI) anchor. Some PIG proteins are components of the GPI transamidase complex and play a role in the recognition of either the GPI attachmentsignal or the lipid portion of GPI. Other PIGs belong to the glycosyltransferase complex and function in the transfer of N-acetylglucosamine (GlcNAc) to phosphatidyli nositol (PI). A variety of other PIGs play distinct rolesin GPIsynthesis. PIG-F functions as an auxiliary subunit of ethanolamine phosphate (EtNP) transferases. It associates with PIG-O and isrequired for its expression and stability. Together these two PIGs function as an EtNP transferase and catalyze the transfer of EtNP to the third mannose (Man-3) of GPI. Amutation in the gene encoding PIG-F may result in a block of EtNP addition to Man-3 and lead to an absence of GPI-anchored proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIGF
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PIGF
Gene Accession No. Q07326
Gene Alias GPI11 homolog; phosphatidylinositol glycan anchor biosynthesis class F; phosphatidylinositol glycan anchor biosynthesis, class F; phosphatidylinositol glycan, class F; phosphatidylinositol-glycan biosynthesis class F protein; phosphatidylinositol-glycan biosynthesis class protein-like protein; PIGF; PIG-F; Unknown (protein for MGC:133893)
Gene Symbols PIGF
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PIGF. Recombinant protein control fragment (Product #RP-101375).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5281
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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