Invitrogen™ PIGW Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537196

Catalog No. PIPA537196

Description

This antibody detects endogenous protein at a molecular weight of 57 kDa. Purity is >95% by SDS-PAGE.

Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins that localize to the endoplasmic reticulum. PIGs exhibit various functions, but all are crucial for the biosynthesis of the glycosylphosphatidylinositol (GPI)-anchor. Some PIG proteins are components of the GPI transamidase complex and play a role in the recognition of either the GPI attachment signal or the lipid portion of GPI. Other PIGs belong to the glycosyltransferase complex and function in the transfer of N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI). A variety of other PIGs play distinct roles in GPI synthesis including mannosylation of the GPI-anchor. PIG-W (Phosphatidylinositol-glycan biosynthesis class W protein) is a 504 amino acid multi-pass membrane protein that functions in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol.

Specifications

• Antigen: PIGW
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PIGW
• Gene Alias: 2610044A17Rik; Gwt1; HPMRS5; phosphatidylinositol glycan anchor biosynthesis class W; phosphatidylinositol glycan anchor biosynthesis, class W; phosphatidylinositol glycan, class W; phosphatidylinositol-glycan biosynthesis class W protein; Pigw; PIG-W
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 284098, 378774, 70325
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q7TSN4, Q7Z7B1, Q8C398
• Gene Symbols: PIGW
• Immunogen: A synthetic peptide corresponding to residues in human PIGW.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG