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Invitrogen™ PIGW Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537196

Catalog No. PIPA537196


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Description

Description

This antibody detects endogenous protein at a molecular weight of 57 kDa. Purity is >95% by SDS-PAGE.

Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins that localize to the endoplasmic reticulum. PIGs exhibit various functions, but all are crucial for the biosynthesis of the glycosylphosphatidylinositol (GPI)-anchor. Some PIG proteins are components of the GPI transamidase complex and play a role in the recognition of either the GPI attachment signal or the lipid portion of GPI. Other PIGs belong to the glycosyltransferase complex and function in the transfer of N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI). A variety of other PIGs play distinct roles in GPI synthesis including mannosylation of the GPI-anchor. PIG-W (Phosphatidylinositol-glycan biosynthesis class W protein) is a 504 amino acid multi-pass membrane protein that functions in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PIGW
Polyclonal
Unconjugated
PIGW
2610044A17Rik; Gwt1; HPMRS5; phosphatidylinositol glycan anchor biosynthesis class W; phosphatidylinositol glycan anchor biosynthesis, class W; phosphatidylinositol glycan, class W; phosphatidylinositol-glycan biosynthesis class W protein; Pigw; PIG-W
Rabbit
Antigen Affinity Chromatography
RUO
284098, 378774, 70325
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Q7TSN4, Q7Z7B1, Q8C398
PIGW
A synthetic peptide corresponding to residues in human PIGW.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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